Zavicefta 2 g/0.5 g Powder for Infusion is an advanced combination antibiotic developed by Pfizer, containing ceftazidime and avibactam. Zavicefta 2 g/0.5 g is specifically formulated to combat severe and multi-drug resistant bacterial infections. Zavicefta 2 g/0.5 g is widely used in hospital settings for treating complicated intra-abdominal infections (cIAI), complicated urinary tract infections (cUTI), hospital-acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP), and infections caused by aerobic Gram-negative bacteria in adult and pediatric patients.
Ceftazidime in Zavicefta 2 g/0.5 g is a third-generation cephalosporin antibiotic, while Avibactam is a non-beta-lactam beta-lactamase inhibitor that protects ceftazidime from enzymatic degradation. Together, this combination makes Zavicefta 2 g/0.5 g a highly effective treatment option against extended-spectrum beta-lactamase (ESBL) producing and carbapenem-resistant Enterobacteriaceae (CRE).
Key Benefits and Uses of Zavicefta 2 g/0.5 g:
- Effective against multidrug-resistant Gram-negative bacterial infections.
- Treats complicated intra-abdominal infections (cIAI).
- Used for complicated urinary tract infections (cUTI), including pyelonephritis.
- Indicated for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP).
- Active against pathogens resistant to other antibiotics, including carbapenem-resistant strains.
Dosage and Administration:
Zavicefta 2 g/0.5 g Powder for Infusion is administered intravenously (IV) over 2 hours. The dosage is determined by a healthcare professional based on the severity of the infection, renal function, and patient’s clinical condition. Zavicefta 2 g/0.5 g is typically reconstituted and diluted before intravenous infusion.
Storage Instructions:
- Store Zavicefta 2 g/0.5 g Powder in its original packaging below 25°C.
- Protect from light and moisture.
- Reconstituted solutions should be used immediately or stored under refrigeration as advised.
Possible Side Effects:
While Zavicefta 2 g/0.5 g is generally well-tolerated, potential side effects include:
- Nausea and vomiting.
- Diarrhea.
- Headache.
- Elevated liver enzymes.
- Hypersensitivity reactions.
Serious side effects like Clostridium difficile-associated diarrhea or anaphylaxis are rare but require immediate medical attention.
Why Choose Zavicefta 2 g/0.5 g?
- Combination of ceftazidime and avibactam for superior efficacy.
- Effective against multi-drug resistant Gram-negative pathogens.
- Trusted quality from Pfizer.
- Recommended by infectious disease specialists worldwide.
Product Contents:
Each box contains:
- 10 vials of Zavicefta 2 g/0.5 g Powder for Infusion (Ceftazidime/Avibactam).
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