What is Ursactive 250 mg?
Ursactive 250 mg contains Ursodeoxycholic Acid (UDCA), a bile acid widely used for the treatment of gallstone disease, primary biliary cholangitis (PBC), and liver disorders. Manufactured by Humanis, Ursactive helps improve liver function by reducing bile cholesterol levels and protecting liver cells from damage.
This medication is commonly prescribed for patients with liver dysfunction, gallbladder problems, and cholestatic liver diseases. It is also used in cystic fibrosis-related liver disease and some metabolic conditions that affect bile flow.
How Does Ursactive Work?
Ursodeoxycholic Acid (UDCA) works through multiple mechanisms:
✔️ Dissolves cholesterol-based gallstones by reducing cholesterol concentration in bile.
✔️ Protects liver cells (hepatocytes) from damage by decreasing toxic bile acid accumulation.
✔️ Improves bile flow in patients with cholestatic liver diseases.
✔️ Reduces liver inflammation and fibrosis in chronic liver conditions.
✔️ Used as adjunct therapy for certain autoimmune liver diseases such as primary biliary cholangitis (PBC).
Indications: What Conditions Does Ursactive Treat?
Ursactive 250 mg is commonly prescribed for:
✔️ Gallstones (Cholesterol-type stones) – Helps dissolve small, non-calcified gallstones in patients who cannot undergo surgery.
✔️ Primary Biliary Cholangitis (PBC) – Reduces liver damage by promoting bile flow.
✔️ Liver Cirrhosis & Chronic Liver Disease – Supports liver function in hepatitis and cirrhosis patients.
✔️ Cystic Fibrosis-related Liver Disease – Enhances bile secretion in patients with cystic fibrosis.
✔️ Non-Alcoholic Fatty Liver Disease (NAFLD) – Helps improve liver enzyme levels.
Dosage & Administration: How to Use Ursactive?
- Formulation: 250 mg capsule
- Administration: Oral use (swallowed whole with water)
- Recommended Dosage:
- Gallstones: 8-10 mg/kg/day, divided into 2-3 doses for 6-24 months
- Primary Biliary Cholangitis (PBC): 13-15 mg/kg/day, once daily or in divided doses
- Liver Disorders & Bile Flow Issues: Dosage varies based on condition (consult a doctor)
- Food Requirement: Take with food for better absorption
Side Effects of Ursactive
Although well tolerated, some potential side effects include:
- Common Side Effects: Mild diarrhea, nausea, upset stomach, dizziness.
- Rare Side Effects: Severe itching, allergic reactions, worsening liver function (in rare cases).
Why Choose Ursactive Over Other UDCA Medications?
✔️ Highly effective in gallstone dissolution and liver protection.
✔️ Clinically proven benefits for cholestatic liver diseases.
✔️ Better tolerability with fewer gastrointestinal side effects.
✔️ Trusted by healthcare professionals worldwide.
Precautions & Warnings
⚠️ Not recommended for calcified gallstones or severe liver failure.
⚠️ Pregnant or breastfeeding women should consult a doctor before use.
⚠️ Patients with chronic liver disease should have liver function tests regularly.
⚠️ Avoid use in severe kidney impairment.
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