Erivedge 150 mg is a pioneering oral medication developed by Roche, containing the active ingredient Vismodegib, specifically designed for the treatment of advanced basal cell carcinoma (BCC). As the first FDA-approved Hedgehog pathway inhibitor, Erivedge revolutionized the therapeutic landscape for patients with locally advanced or metastatic basal cell carcinoma who are not suitable candidates for surgery or radiation.
Key Product Details:
- Active Ingredient: Vismodegib 150 mg
- Form: Hard Capsules
- Route of Administration: Oral
- Packaging: 28 Capsules
- Manufacturer: Roche
Key Benefits of Erivedge 150 mg:
- Targeted Therapy: Inhibits the Hedgehog signaling pathway, which is abnormally activated in basal cell carcinoma.
- Treatment for Advanced BCC: Effective for patients with locally advanced BCC or metastatic BCC when surgery or radiation is not suitable.
- Convenient Oral Capsule: Easy-to-administer, once-daily capsule.
- High Response Rate: Clinical trials show significant tumor reduction and disease control rates.
How Does Erivedge Work?
Erivedge (Vismodegib) targets and inhibits a key protein called Smoothened (SMO) within the Hedgehog signaling pathway. This pathway is essential for cell growth and differentiation, but abnormal activation leads to the development and progression of basal cell carcinoma.
- Pathway Inhibition: Blocks the Hedgehog signaling pathway by binding to the Smoothened protein.
- Tumor Growth Suppression: Stops the uncontrolled proliferation of cancerous basal cells.
- Reduction of Lesions: Helps reduce the size of tumors and skin lesions in advanced BCC.
Indications:
- Locally Advanced BCC: When surgery or radiation therapy is deemed inappropriate.
- Metastatic BCC: In cases where the cancer has spread to other parts of the body.
Dosage and Administration:
- Recommended Dose: 150 mg capsule once daily.
- Administration: Can be taken with or without food.
- Treatment Duration: Continue until disease progression or unacceptable toxicity.
Safety Information:
- Common Side Effects: Muscle spasms, alopecia, taste disturbances, fatigue, weight loss, nausea, diarrhea.
- Pregnancy Warning: Highly teratogenic – can cause severe birth defects. Effective contraception is mandatory during treatment and for 24 months after the last dose.
- Fertility Concerns: May affect fertility in both men and women.
- Blood Donation: Not allowed during treatment and for 24 months after stopping the medication.
Why Choose Erivedge 150 mg?
Erivedge 150 mg is a breakthrough therapy for patients with advanced basal cell carcinoma who have limited treatment options. Its targeted mechanism of action, combined with oral convenience and proven efficacy, makes it the first choice for patients and oncologists seeking non-invasive alternatives to surgery and radiation.
Storage Conditions:
- Temperature: Store at room temperature (15°C to 30°C).
- Packaging: Keep in original blister pack to protect from moisture.
Buy Erivedge 150 mg Online:
Looking for a reliable source to buy Erivedge 150 mg (Vismodegib)? We supply genuine Roche products with fast and secure international delivery. Ensure you get the best treatment options for advanced BCC.
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